The event's original main event featured Khamzat Chimaev against Nate Diaz. However, Chimaev missed weight by 7.5 pounds (weighing 178.5 lbs), forcing a complete overhaul of the top three fights just 24 hours before the event. Original Fight New UFC 279 Fight Key Outcome Nate Diaz vs. Tony Ferguson Diaz via Sub (R4) Tony Ferguson vs. Li Jingliang Khamzat Chimaev vs. Kevin Holland Chimaev via Sub (R1) Kevin Holland vs. Daniel Rodriguez Daniel Rodriguez vs. Li Jingliang Rodriguez via Split Dec Main Card Results

UFC 279, held on September 10, 2022, is primarily remembered for a chaotic last-minute card reshuffle following a major weight miss and backstage altercations. The event, headlined by Nate Diaz's final promotional appearance, transitioned from a heavily criticized mismatch into a celebrated double-legend feature.