This means the game file isn't locked to a specific part of the world (like NTSC for North America or PAL for Europe). You can run it on compatible hardware or emulators regardless of where you bought your console.
Ensure the file ends in .iso . Never run a .exe file that claims to be a game console image. NBA 2K16 [Region Free][ISO]
While newer titles have flashier graphics, 2K16 is often cited as the peak of the series for several reasons: This means the game file isn't locked to
If you're running this on an original console, it usually requires a "soft-mod" (like Brew on PS3) to boot ISO files directly from a hard drive. A Quick Warning on Safety NBA 2K16 [Region Free][ISO]